Clinical Trials Search at Vanderbilt-Ingram Cancer Center

Neuroblastoma Maintenance Therapy Trial

Multiple Cancer Types

Difluoromethylornithine (DFMO) will be used in an open label, single agent, multicenter,
study for patients with neuroblastoma in remission. In this study subjects will receive 730
Days of oral difluoromethylornithine (DFMO) at a dose of 750 mg/m2 250 mg/m2 BID (strata 1,
2, 3, and 4) OR 2500 mg/m2 BID (stratum 1B) on each day of study. This study will focus on
the use of DFMO in high risk neuroblastoma patients that are in remission as a strategy to
prevent recurrence.

Disease Sites: Endocrine, Neuroblastoma (Pediatrics), Neuroendocrine, Pediatrics

Phase: II

Investigator: Pastakia, Devang

NCTID: NCT02679144

Protocol No: VICCPED16157

Improving Care after Inherited Cancer Testing (IMPACT) Study

Miscellaneous

This clinical trial investigates factors associated with access to genetic risk assessment, counseling, and testings services. The trial also seeks to refine and evaluate the effectiveness of online tools on improving cancer risk management practices and family communication of genetic test results.

Disease Sites: Miscellaneous

Phase: N/A

Investigator: Pal, Tuya

NCTID: NCT04763915

Protocol No: VICCSUPP2112

A Real-World Study to Observe Outcomes of Patients Undergoing Closure with the Amplatzer™ Amulet™ Left Atrial Appendage Occluder
ADVANCE

Disease Sites: Not Available

Phase:

Investigator: Baker, Michael

NCTID: NCT05997446

Protocol No: CRE-ARR0021

CORCINCH-HF Study - Randomized Clinical Evaluation of the AccuCinch Ventricular Restoration System in Patients who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF)

Disease Sites: Not Available

Phase: III

Investigator: Barker, Colin

NCTID: NCT04331769

Protocol No: CRE-INT0004

Molecular Predictors of Lung Cancer Behavior. (SPORE)

Multiple Cancer Types

Disease Sites: Lung, Non Small Cell, Small Cell

Phase: N/A

Investigator: Maldonado, Fabien

NCTID: NCT00898313

Protocol No: VICCTHO0398

PEERLESS Study A prospective, multicenter, randomized controlled trial of the FlowTriever System compared to Catheter-Directed Thrombolysis (CDT) for use in the treatment of acute pulmonary embolism. The trial includes a non-randomized cohort of subjects with an absolute contraindication to thrombolysis.

Disease Sites: Not Available

Phase: III

Investigator: Fong, Pete

NCTID: NCT05111613

Protocol No: CRE-INT0007

CLASP IID/IIF

Disease Sites: Not Available

Phase: N/A

Investigator: Barker, Colin

NCTID: NCT03706833

Protocol No: VALV0005

Abbott Ventricular Tachycardia Post Approval Study

Disease Sites: Not Available

Phase: N/A

Investigator: Tandri, Harikrishna

NCTID: NCT05839873

Protocol No: CRE-INT0011

CATALYST Trial - Clinical trial of atrial fibrillation patients comparing left atrial appendage occlusion therapy to non-vitamin K antagonist oral anticoagulants

Disease Sites: Not Available

Phase:

Investigator: Baker, Michael

NCTID: NCT04226547

Protocol No: CRE-ARR0005

A Randomized, Open-Label Pilot Trial to Evaluate the Safety and Efficacy of Carmustine Wafer in Combination with Retifanlimab and Standard Radiation With or Without Temozolomide in Newly-Diagnosed Adult Subjects with Glioblastoma

Multiple Cancer Types

Disease Sites: Neuro-Oncology, Phase I

Phase: I

Investigator: Thompson, Reid

NCTID: NCT05083754

Protocol No: VICCNEUP22119

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