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Gastrointestinal Cancer Research Program

Gastrointestinal (GI) cancers remain some of the most difficult to treat, with five-year survival rates below 50 percent for most GI cancer types.

The Gastrointestinal Cancer Research Program aims to better understand what drives these cancers with the goal of identifying and applying better treatment strategies. Our research efforts span the entire spectrum—from in-depth basic research to investigator-initiated clinical trials—across all GI cancer types, including colorectal, gastroesophageal, and pancreatic cancers.

RESEARCH THEMES

The Gastrointestinal Cancer Program supports basic, translational and clinical research across all GI cancer types:

Determining the etiology and pathogenesis of gastrointestinal cancers

Developing biomarkers and imaging techniques to improve detection and predict efficacy of current and novel therapeutics for gastrointestinal cancers

Developing and studying novel laboratory models of cancer to improve understanding of human cancers

Translating laboratory discoveries into clinical investigations

Meet the Program Members

R. Daniel Beauchamp, M.D., and Cathy Eng, M.D., are co-leaders of the GI Cancer Research Program. The program has more than 30 members conducting clinical and translational research on a range of gastrointestinal cancers, with particular focus on colorectal, gastroesophageal and pancreas cancers.  


Featured Publications

Program News

January 16, 2020

VUMC study sheds light on gastric cancer development

VUMC researchers have created the world’s first laboratory model of precancerous changes in the lining of the stomach, a scientific tour de force that is helping to unlock the mysteries of gastric cancer development.
November 1, 2019

New Physician Spotlight: Cathy Eng

Cathy Eng, MD, a national and international leader in gastrointestinal medical oncology, was recruited to VUMC from The University of Texas MD Anderson Cancer Center in Houston.
October 3, 2019

A step toward gastric cancer

New research findings provide insight into the detrimental events that develop in response to H. pylori infection.