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Lung cancer metastasis-National Cancer Institute \ Winship Cancer Institute of Emory University

Host-Tumor Interactions Research Program

Tumor growth, invasion, and metastasis depend not only on the tumor cell alone, but also on the complex interactions between the tumor cells and their host. The goal of the Host-Tumor Interactions Research Program is to develop a detailed and mechanistic understanding of not just the tumor cell and tumor mutations, but also all the components of the host microenvironment that influence cancer and the response to cancer therapy.

RESEARCH THEMES

With the goal of understanding how complex interactions between tumor cells and their host contribute to cancer, the Host-Tumor Interactions program focuses on four specific research themes:

Understanding how new blood vessels form to feed tumors – and finding ways to block these processes

Identifying molecules involved in communication between tumor cells and their cellular and structural microenvironment

Uncovering how inflammation triggers and promotes cancer

Integrating knowledge about host-tumor interactions to understand how tumors evolve in a changing microenvironment

Meet the Program Members

The Host-Tumor Interactions program is co-led by Mary M. Zutter, M.D., and Jeffrey Rathmell, Ph.D. The basic, translational, and clinical scientists who make up this program are focused on discovering and understanding these interactions, with the ultimate goal of developing strategies to control tumor progression and metastasis by targeting these interactions.


Featured Publications

Program News

June 15, 2018

Karijolich named 2018 Pew Biomedical Scholar

John Karijolich, PhD, a member of the cancer center's Host-Tumor Interactions Research Program, has been named a Pew Biomedical Scholar by The Pew Charitable Trusts. His laboratory investigates viruses associated with human cancer.
June 12, 2018

$8.1 million grant funds new center to research highly aggressive form of lung cancer

The grant from the National Cancer Institute, establishes a research center for advancing the understanding and treatment of small cell lung cancer. Vito Quaranta, M.D.

Seminars & Events

Calendar
Sep
13
VICC Seminar Series: Steve Patierno, PhD

13 September 2018

Calendar
Nov
08
VICC Seminar/Discovery Lecture: Stephen Baylin, MD

08 November 2018

Calendar
Apr
25
VICC Seminar Series: Lisa Coussens, PhD

25 April 2019