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Translational Research and Interventional Oncology Research Program

The Translational Research and Interventional Oncology Research Program translates advances in mechanism-based research into improved detection methods and therapies for cancer. With a primary focus on lung cancer, melanoma and leukemia/lymphoma, the program is dedicated to new discoveries in early detection and molecular oncology, and genotype-driven early phase trials for all cancer types.

RESEARCH THEMES

The Translational Research and Interventional Oncology program is dedicated to translating our understanding of the molecular mechanisms of oncogenesis and tumor progression into novel therapeutic strategies for cancer. 

Developing early phase clinical trials for therapies directed at genetic changes in tumors

Investigating why some tumors become resistant to genetically targeted therapies and developing new strategies to prevent and overcome resistance

Applying and enhancing immune strategies and cellular therapies for cancer

Developing and evaluating screening methods and biomarkers for early detection of lung cancers

Meet the Program Members

The Translational Research and Interventional Oncology Program is the largest of the cancer center's formal research programs, with more than 50 members representing a range of clinical and translational cancer research areas. The program is led by Madan Jagasia, M.B.B.S., Young Kim, M.D., Ph.D., and Christine Lovly, M.D., Ph.D.

Featured Publications

Program News

December 1, 2018

Teamwork key to treating patient’s rare blood cancer

Patient Joe Lofaro credits the teamwork of Nishitha Reddy, MBBS, MSCI, and other clinicians at VUMC for diagnosing him with the rare blood cancer Erdheim-Chester disease.
December 1, 2018

Lung cancer survival signal

A recent study shows that a cell receptor, SSTR2, is a candidate biomarker for poor prognosis and a potential therapeutic target for small cell lung cancer.

Seminars & Events

Calendar
Nov
30
“The Exosomes in Immune Suppression and Tumor Invasion”

30 November 2018