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Translational Research and Interventional Oncology Research Program

The Translational Research and Interventional Oncology Research Program translates advances in mechanism-based research into improved detection methods and therapies for cancer. With a primary focus on lung cancer, melanoma and leukemia/lymphoma, the program is dedicated to new discoveries in early detection and molecular oncology, and genotype-driven early phase trials for all cancer types.

RESEARCH THEMES

The Translational Research and Interventional Oncology program is dedicated to translating our understanding of the molecular mechanisms of oncogenesis and tumor progression into novel therapeutic strategies for cancer. 

Developing early phase clinical trials for therapies directed at genetic changes in tumors

Investigating why some tumors become resistant to genetically targeted therapies and developing new strategies to prevent and overcome resistance

Applying and enhancing immune strategies and cellular therapies for cancer

Developing and evaluating screening methods and biomarkers for early detection of lung cancers

Meet the Program Members

The Translational Research and Interventional Oncology Program is the largest of the cancer center's formal research programs, with more than 50 members representing a range of clinical and translational cancer research areas. The program is led by Madan Jagasia, M.B.B.S., Young Kim, M.D., Ph.D., and Christine Lovly, M.D., Ph.D.

Featured Publications

Program News

January 18, 2019

Research explores link between stem cell transplant, diabetes

As many as 50 percent of stem cell transplant recipients develop diabetes. Brian Engelhardt, M.D.
January 16, 2019

Grant to help address complexity of cancer care

Jeremy Warner, MD, MS, associate professor of Medicine and Biomedical Informatics, has been awarded a $1 million grant from the National Cancer Institute to develop software that will help clinicians keep up with the increasing complexity of cancer care.
December 1, 2018

Teamwork key to treating patient’s rare blood cancer

Patient Joe Lofaro credits the teamwork of Nishitha Reddy, MBBS, MSCI, and other clinicians at VUMC for diagnosing him with the rare blood cancer Erdheim-Chester disease.

Seminars & Events

TRIO-Events

19 February 2019