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Long Term Follow-up for Early Detection of Lung Cancer in Current or Former Smokers

Lung

This research trial studies the long term follow-up for early detection of lung cancer in current or former smokers. Following up on smokers by collecting and analyzing specimens in the laboratory, performing chest computed tomography (CT) scans, as well as reviewing medical records may help doctors detect lung cancer at an earlier stage.
Lung
N/A
Grogan, Eric
NCT03181256
VICCTHO1730

Molecular Predictors of Lung Cancer Behavior. (SPORE)

Multiple Cancer Types

Lung, Non Small Cell, Small Cell
N/A
Maldonado, Fabien
NCT00898313
VICCTHO0398

Molecular Fingerprinting of Lung Cancer (SPORE)

Multiple Cancer Types

Lung, Non Small Cell
N/A
Grogan, Eric
NCT00897117
VICCTHO0136

Lung Cancer Screening Program at VICC: Correlative Study

Lung

Lung
N/A
Sandler, Kim
VICCTHO1496

Using Biomarkers and Imaging in Fungal Regions to Improve Lung Cancer Diagnosis

Lung

Lung
N/A
Grogan, Eric
VICCTHO1764

Nashville Biosciences Blood Sample Collection Study

Multiple Cancer Types

Colon, Liver, Lung, Non Small Cell, Ovarian, Pancreatic, Rectal
N/A
Bernard, Gordon
VICCMD18123

Cancer Patient Safety Learning Laboratory (CaPSLL): Preventing Clinical Deterioration in Outpatients

Multiple Cancer Types

Head/Neck, Lung
N/A
Weinger, Matthew
VICCMD1998

Validating an Integrated Biomarker and Imaging Approach in the Evaluation of Indeterminate Pulmonary Nodules.

Lung

Lung
N/A
Grogan, Eric
VICCTHO2002

Liquid Biopsy of The Lung to Profile Lung Cancer

Lung

Lung
N/A
Maldonado, Fabien
VICCTHO2107

Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

Multiple Cancer Types

This phase III trial studies whether pembrolizumab alone as a first-line treatment, followed by pemetrexed and carboplatin with or without pembrolizumab after disease progression is superior to induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the bodys immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Drugs used in chemotherapy, such as pemetrexed and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known whether giving first-line pembrolizumab followed by pemetrexed and carboplatin with or without pembrolizumab works better in treating patients with non-squamous non-small cell cancer.
Lung, Non Small Cell
III
York, Sally
NCT03793179
ECOGTHOEA5163