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Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

Multiple Cancer Types

The purpose of this study is to find out whether the study drug, LY3537982, is safe and effective in cancer patients who have a specific genetic mutation (KRAS G12C). Patients must have already received or were not able to tolerate the standard of care. The study will last up to approximately 2 years.
Colon, Gastrointestinal, Lung, Miscellaneous, Non Small Cell, Phase I, Rectal
I
Iams, Wade
NCT04956640
VICCTHOP2155

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

Breast

The purpose of this study is to further advance the ability to practice personalized medicine by learning which new drug agents are most effective with which types of breast cancer tumors and by learning more about which early indicators of response (tumor analysis prior to surgery via magnetic resonance imaging (MRI) images along with tissue and blood samples) are predictors of treatment success.
Breast
II
Kennedy, Laura
NCT01042379
VICCBRE1951