
Daniel B. Brown, M.D.
- Professor of Radiology and Radiological Sciences
- Director, Interventional Oncology
Phone
1161-21st Avenue S.
CCC-1118 Medical Center North
Nashville, TN 37232-2675
Daniel B. Brown, M.D.
- Professor of Radiology and Radiological Sciences
- Director, Interventional Oncology
615-322-3906
daniel.b.brown@vumc.org
1161-21st Avenue S.
CCC-1118 Medical Center North
Nashville, TN 37232-2675
Research Program
Departments/Affiliations
Provider Information
Profile
Dr. Brown focuses his clinical work on Interventional Oncology, a subspecialty which uses imaging to guide minimally invasive cancer treatments. He treats both primary and metastatic tumors to the liver with radioactive beads and chemoembolization. Treated tumor types include hepatocellular carcinoma, cholangiocarcinoma, neuroendocrine tumor, colorectal cancer, breast cancer, melanoma, and soft tissue sarcoma.
He also treats liver, kidney, skeletal and lung tumors with ablative techniques, including cryoablation as well as radiofrequency and microwave ablation. Painful skeletal masses may also be treatable with vertebroplasty.
Dr. Brown has authored over 100 articles and scientific abstracts and has written performance guidelines for a number of the minimally-invasive oncologic interventions done at Vanderbilt. His research has focused on the entire spectrum of interventional oncology.
Education
- Fellowship: Penn State University, 1997-1999
- Faculty: Washington University in St. Louis, 1999-2007
- Faculty: Thomas Jefferson University, 2007-2013
Research Emphasis
Research Description
Publications
- Cruz JC, Watchmaker JM, Albin MM, Wang L, Wu G, Baker JC, Fritsche MR, Alexopoulos SP, Matsuoka L, Fleming JW, Su J, Borgmann AJ, Banovac F, Brown DB. Neutrophil/Lymphocyte Ratio Predicts Increased Risk of Immediate Progressive Disease following Chemoembolization of Hepatocellular Carcinoma. J Vasc Interv Radiol [print-electronic]. 2019 Oct 10/24/2019; PMID: 31669086, PII: S1051-0443(19)30686-4, DOI: 10.1016/j.jvir.2019.08.001, ISSN: 1535-7732.
- Hevert EAC, Howser CG, Gould ML, Brown DB. Ablative, Endovascular, and Biliary Interventions for Patients with Pancreatic Cancer. Semin Intervent Radiol [print-electronic]. 2019 Aug; 36(3): 203-12. PMID: 31435128, PMCID: PMC6699965, PII: 001149, DOI: 10.1055/s-0039-1693118, ISSN: 0739-9529.
- Klimkowski S, Baker JC, Brown DB. Red Flags, Pitfalls, and Cautions in Y90 Radiotherapy. Tech Vasc Interv Radiol [print-electronic]. 2019 Jun; 22(2): 63-9. PMID: 31079712, PII: S1089-2516(19)30012-5, DOI: 10.1053/j.tvir.2019.02.005, ISSN: 1557-9808.
- Perez AW, Watchmaker JM, Brown DB, Banovac F. Association between Periprocedural Neutropenia and Early Infection-related Chest Port Removal. Radiology [print-electronic]. 2019 May; 291(2): 513-8. PMID: 30747596, DOI: 10.1148/radiol.2019182175, ISSN: 1527-1315.
- Watchmaker JM, Lipnik AJ, Fritsche MR, Baker JC, Mouli SK, Geevarghese S, Banovac F, Omary RA, Brown DB. Are prophylactic antibiotics necessary prior to transarterial chemoembolization for hepatocellular carcinoma in patients with native biliary anatomy?. J Surg Oncol [print-electronic]. 2018 May; 117(6): 1312-7. PMID: 29513895, DOI: 10.1002/jso.24993, ISSN: 1096-9098.
- Fritsche MR, Watchmaker JM, Lipnik AJ, Baker JC, Geevarghese S, Banovac F, Omary RA, Brown DB. Outpatient Transarterial Chemoembolization of Hepatocellular Carcinoma: Review of a Same-Day Discharge Strategy. J Vasc Interv Radiol [print-electronic]. 2018 Feb 2/23/2018; PMID: 29478795, PII: S1051-0443(17)31038-2, DOI: 10.1016/j.jvir.2017.11.018, ISSN: 1535-7732.
- Mouli S, Baker JC, Brown DB. Interventional Oncology Service Development. Semin Intervent Radiol [print-electronic]. 2017 Jun; 34(2): 182-6. PMID: 28579686, PMCID: PMC5453768, PII: 00999, DOI: 10.1055/s-0037-1601853, ISSN: 0739-9529.
- Taussig MD, Irene Koran ME, Mouli SK, Ahmad A, Geevarghese S, Baker JC, Lipnik AJ, Banovac F, Brown DB. Neutrophil to lymphocyte ratio predicts disease progression following intra-arterial therapy of hepatocellular carcinoma. HPB (Oxford) [print-electronic]. 2017 Feb 2/9/2017; PMID: 28190710, PII: S1365-182X(17)30043-6, DOI: 10.1016/j.hpb.2017.01.013, ISSN: 1477-2574.
- Koran ME, Stewart S, Baker JC, Lipnik AJ, Banovac F, Omary RA, Brown DB. Five percent dextrose maximizes dose delivery of Yttrium-90 resin microspheres and reduces rates of premature stasis compared to sterile water. Biomed Rep [print-electronic]. 2016 Dec; 5(6): 745-8. PMID: 28105342, PMCID: PMC5228356, PII: BR-0-0-799, DOI: 10.3892/br.2016.799, ISSN: 2049-9434.
- Koran ME, Lipnik AJ, Baker JC, Banovac F, Omary RA, Brown DB. Procedural Impact of a Dedicated Interventional Oncology Service Line in a National Cancer Institute Comprehensive Cancer Center. J Am Coll Radiol [print-electronic]. 2016 Jun 6/11/2016; PMID: 27297700, PII: S1546-1440(16)30307-6, DOI: 10.1016/j.jacr.2016.04.033, ISSN: 1558-349X.